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North America CAR-T Cell Therapy Treatment Market - Industry Trends and Forecast to 2028
- Published Date: September, 2022 | Report ID: CLS-289 | No of pages: 160 | Format:
North America CAR-T cell therapy treatment market is projected to register a CAGR of 29.9% in the forecast period of 2021 to 2028. The new market report contains data for the historic year 2019, the base year of calculation is 2020 and the forecast period is 2021 to 2028.
Market Segmentation:
North America CAR-T Cell Therapy Treatment Market, By Product (Autologous CAR-T Cells, Allogeneic CAR-T Cells), Structure (First Generation CAR-T Cells, Second Generation Car-T Cells, Third Generation CAR-T Cells, Fourth Generation CAR-T Cells), Targeted Antigens (Antigens on Solid Tumors, Antigens on Hematologic Malignancies, Others), Brand (Yescarta, Kymriah, Tecartus, Others), Therapeutic Application (Hematological Malignancies, Pancreatic Cancer, Breast Cancer, Lung Cancer, Gastric Cancer, Multiple Myeloma, Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B-Cell Lymphoma, Acute Lymphoblastic Leukemia, Others), End User (Hospitals, Specialty Clinics, Others), Distribution Channel (Hospitals Pharmacy, Others), Country (U.S, Canada and Mexico) Industry Trends and Forecast to 2028
Some of the major factors contributing to the growth of global CAR-T cell therapy treatment market are:
Increase in usage of CAR-T cell therapy for the treatment of cancer and infectious diseases
Rise in awareness about immunotherapies
Market Players:
The key market players for North America CAR-T cell therapy treatment market are listed below:
Atara Biotherapeutics, Inc.
Amgen Inc.
Bellicum Phamaceuticals, Inc.
bluebird bio, inc.
Adaptimmune Therapeutics plc.
Bristol-Myers Squibb Company
Xyphos (A Subsidiary of Astellas Pharma Inc.)
Johnson & Johnson Services, Inc
BioAtla Inc.
Novartis AG
Kite Pharma (A Subsidiary of Gilead Sciences, Inc.)
Aurora Biopharma
Tmunity Therapeutics
Cartherics Pty ltd
Ziopharm Oncology, Inc.
Cellectis
Mustang Bio
Sorrento Therapeutics, Inc.
TC BIOPHARM
Celyad Oncology
Tessa Therapeutics Ltd
TABLE OF CONTENT
TABLE OF CONTENTS 1 INTRODUCTION 1.1 OBJECTIVES OF THE STUDY 1.2 MARKET DEFINITION 1.3 OVERVIEW OF NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET 1.4 LIMITATIONS 1.5 MARKETS COVERED 2 MARKET SEGMENTATION 2.1 MARKETS COVERED 2.2 GEOGRAPHICAL SCOPE 2.3 YEARS CONSIDERED FOR THE STUDY 2.4 CURRENCY AND PRICING 2.5 DBMR TRIPOD DATA VALIDATION MODEL 2.6 MULTIVARIATE MODELLING 2.7 PRODUCT LIFELINE CURVE 2.8 PRIMARY INTERVIEWS WITH KEY OPINION LEADERS 2.9 DBMR MARKET POSITION GRID 2.10 VENDOR SHARE ANALYSIS 2.11 MARKET PRODUCT COVERAGE GRID 2.12 SECONDARY SOURCES 2.13 ASSUMPTIONS 3 EXECUTIVE SUMMARY 4 PREMIUM INSIGHT 5 EPIDEMIOLOGY 6 PIPELINE ANALYSIS 7 MARKET OVERVIEW 7.1 DRIVERS 7.1.1 INCREASE IN USAGE OF CAR-T CELL THERAPY FOR THE TREATMENT OF CANCER AND INFECTIOUS DISEASES 7.1.2 INCREASING PREVALENCE OF CANCER 7.1.3 RISE IN AWARENESS ABOUT IMMUNOTHERAPIES 7.1.4 INCREASING INVESTMENT IN RESEARCH AND DEVELOPMENT 7.1.5 ADOPTION OF CAR-T CELL THERAPY TREATMENT IN EMERGING MARKETS 7.2 RESTRAINTS 7.2.1 ADVERSE SIDE EFFECTS OF THERAPIES 7.2.2 HIGH COST ASSOCIATED WITH THERAPIES 7.2.3 LOGISTIC CHALLENGE ASSOCIATED WITH CAR-T THERAPIES 7.2.4 AVAILABILITY OF ALTERNATIVES FOR TUMOR TREATMENT 7.3 OPPORTUNITIES 7.3.1 PRESENCE OF PIPELINE PRODUCTS 7.3.2 STRATEGIC INITIATIVES BY MARKET PLAYERS 7.3.3 RISE IN EXPENDITURE IN HEALTHCARE SECTOR 7.4 CHALLENGES 7.4.1 LONG APPROVAL TIME FOR IMMUNOTHERAPIES 7.4.2 LACK OF SKILLED PROFESSIONALS 8 IMPACT OF COVID-19 ON NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET 8.1 IMPACT ON PRICE 8.2 IMPACT ON DEMAND 8.3 IMPACT ON SUPPLY CHAIN 8.4 STRATEGIC DECISION FOR MANUFACTURERS 8.5 CONCLUSION 9 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET, BY PRODUCT 9.1 OVERVIEW 9.2 AUTOLOGOUS CAR-T CELLS 9.3 ALLOGENEIC CAR-T CELLS 10 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET, BY STRUCTURE 10.1 OVERVIEW 10.2 FIRST GENERATION CAR-T CELLS 10.3 SECOND GENERATION CAR-T CELLS 10.4 THIRD GENERATION CAR-T CELLS 10.5 FOURTH GENERATION CAR-T CELLS 11 NORTH AMERICA CAR-T CELL THERAPY TREATMENTMARKET, BY TARGETED ANTIGENS 11.1 OVERVIEW 11.2 ANTIGENS ON HEMATOLOGIC MALIGNANCIES 11.2.1 CLUSTER OF DIFFERENTIATION-19 (CD-19) 11.2.2 CLUSTER OF DIFFERENTIATION-30 (CD-30) 11.2.3 CLUSTER OF DIFFERENTIATION-22 (CD-22) 11.2.4 CLUSTER OF DIFFERENTIATION-20 (CD-20) 11.2.5 CLUSTER OF DIFFERENTIATION-33 (CD-33) 11.3 ANTIGENS ON SOLID TUMORS 11.3.1 HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR-2 (HER-2) 11.3.2 EPIDERMAL GROWTH FACTOR RECEPTORS VARIANT III (EGFRV-III) 11.3.3 MESOTHELIN (MSLN) 11.3.4 PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) 11.3.5 INTERLEUKIN-13RA2 (IL13RA2) 11.3.6 DISIALOGANGLIOSIDE 2 (GD2) 11.3.7 GLYPICAN-3 (GPC3) 11.3.8 OTHERS 11.4 OTHERS 12 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET, BY BRAND 12.1 OVERVIEW 12.2 YESCARTA 12.3 KYMRIAH 12.4 TECARTUS 12.5 OTHERS 13 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET, BY THERAPEUTIC APPLICATION 13.1 OVERVIEW 13.2 FOLLICULAR LYMPHOMA 13.3 DIFFUSE LARGE B-CELL LYMPHOMA 13.4 ACUTE LYMPHOBLASTIC LEUKAEMIA (ALL) 13.5 MANTLE CELL LYMPHOMA 13.6 MULTIPLE MYELOMA 13.7 HEMATOLOGIC MALIGNANCIES 13.7.1 LEUKEMIA 13.7.2 LYMPHOMA 13.7.3 MYELOMA 13.7.4 OTHERS 13.8 LUNG CANCER 13.9 CHRONIC LYMPHOCYTIC LEUKEMIA 13.10 GASTRIC CANCER 13.11 PANCREATIC CANCER 13.12 BREAST CANCER 13.13 OTHERS 14 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET, BY END USER 14.1 OVERVIEW 14.2 HOSPITALS 14.3 SPECIALTY CLINICS 14.4 OTHERS 15 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET, BY DISTRIBUTION CHANNEL 15.1 OVERVIEW 15.2 HOSPITAL PHARMACY 15.3 OTHERS 16 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET BY GEOGRAPHY 16.1 NORTH AMERICA 16.1.1 U.S 16.1.2 CANADA 16.1.3 MEXICO 17 NORTH AMERICA CAR-T CELL THERAPY TREATMENT MARKET: COMPANY LANDSCAPE 17.1 COMPANY SHARE ANALYSIS: NORTH AMERICA 18 SWOT ANALYSIS 19 COMPANY PROFILE 19.1 KITE PHARMA (A SUBSIDIARY OF GILEAD SCIENCES, INC.) 19.1.1 COMPANY SNAPSHOT 19.1.2 REVENUE ANALYSIS 19.1.3 COMPANY SHARE ANALYSIS 19.1.4 PRODUCT PORTFOLIO 19.1.5 RECENT DEVELOPMENTS 19.2 NOVARTIS AG 19.2.1 COMPANY SNAPSHOT 19.2.2 REVENUE ANALYSIS 19.2.3 COMPANY SHARE ANALYSIS 19.2.4 PRODUCT PORTFOLIO 19.2.5 RECENT DEVELOPMENTS 19.3 ABBVIE INC. 19.3.1 COMPANY SNAPSHOT 19.3.2 REVENUE ANALYSIS 19.3.3 PRODUCT PORTFOLIO 19.3.4 RECENT DEVELOPMENTS 19.4 ADAPTIMMUNE THERAPEUTICS PLC 19.4.1 COMPANY SNAPSHOT 19.4.2 REVENUE ANALYSIS 19.4.3 PRODUCT PORTFOLIO 19.4.4 RECENT DEVELOPMENTS 19.5 AMGEN INC. 19.5.1 COMPANY SNAPSHOT 19.5.2 REVENUE ANALYSIS 19.5.3 PIPELINE PRODUCT PORTFOLIO 19.5.4 RECENT DEVELOPMENTS 19.6 ATARA BIOTHERAPEUTICS, INC. 19.6.1 COMPANY SNAPSHOT 19.6.2 PIPELINE PRODUCT PORTFOLIO 19.6.3 RECENT DEVELOPMENTS 19.7 AURORA BIOPHARMA 19.7.1 COMPANY SNAPSHOT 19.7.2 PIPELINE PRODUCT PORTFOLIO 19.7.3 RECENT DEVELOPMENTS 19.8 AUTOLUS 19.8.1 COMPANY SNAPSHOT 19.8.2 PRODUCT PORTFOLIO 19.8.3 RECENT DEVELOPMENTS 19.9 BELLICUM PHAMACEUTICALS, INC. 19.9.1 COMPANY SNAPSHOT 19.9.2 REVENUE ANALYSIS 19.9.3 PRODUCT PORTFOLIO 19.9.4 RECENT DEVELOPMENTS 19.10 BIOATLA INC. 19.10.1 COMPANY SNAPSHOT 19.10.2 PRODUCT PORTFOLIO 19.10.3 RECENT DEVELOPMENTS 19.11 BLUEBIRD BIO, INC. 19.11.1 COMPANY SNAPSHOT 19.11.2 REVENUE ANALYSIS 19.11.3 PRODUCT PORTFOLIO 19.11.4 RECENT DEVELOPMENTS 19.12 BRISTOL-MYERS SQUIBB COMPANY 19.12.1 COMPANY SNAPSHOT 19.12.2 REVENUE ANALYSIS 19.12.3 PRODUCT PORTFOLIO 19.12.4 RECENT DEVELOPMENTS 19.13 CARINA BIOTECH 19.13.1 COMPANY SNAPSHOT 19.13.2 PRODUCT PORTFOLIO 19.13.3 RECENT DEVELOPMENTS 19.14 CARTHERICS PTY LTD 19.14.1 COMPANY SNAPSHOT 19.14.2 PRODUCT PORTFOLIO 19.14.3 RECENT DEVELOPMENTS 19.15 CARTESIAN THERAPEUTICS, INC. 19.15.1 COMPANY SNAPSHOT 19.15.2 PIPELINE PRODUCT PORTFOLIO 19.15.3 RECENT DEVELOPMENTS 19.16 CELLECTIS SA 19.16.1 COMPANY SNAPSHOT 19.16.2 REVENUE ANALYSIS 19.16.3 PRODUCT PORTFOLIO 19.16.4 RECENT DEVELOPMENTS 19.17 CELYAD ONCOLOGY SA 19.17.1 COMPANY SNAPSHOT 19.17.2 PIPELINE PRODUCT PORTFOLIO 19.17.3 RECENT DEVELOPMENTS 19.18 JOHNSON & JOHNSON SERVICES, INC. 19.18.1 COMPANY SNAPSHOT 19.18.2 REVENUE ANALYSIS 19.18.3 PRODUCT PORTFOLIO 19.18.4 RECENT DEVELOPMENTS 19.19 SORRENTO THERAPEUTICS, INC. 19.19.1 COMPANY SNAPSHOT 19.19.2 PIPELINE PRODUCT PORTFOLIO 19.19.3 RECENT DEVELOPMENTS 19.20 TC BIOPHARM LIMITED 19.20.1 COMPANY SNAPSHOT 19.20.2 PIPELINE PRODUCT PORTFOLIO 19.20.3 RECENT DEVELOPMENTS 19.21 TESSA THERAPEUTICS LTD. 19.21.1 COMPANY SNAPSHOT 19.21.2 PIPELINE PRODUCT PORTFOLIO 19.21.3 RECENT DEVELOPMENTS 19.22 TMUNITY THERAPEUTICS 19.22.1 COMPANY SNAPSHOT 19.22.2 PIPELINE PRODUCT PORTFOLIO 19.22.3 RECENT DEVELOPMENTS 19.23 MUSTANG BIO 19.23.1 COMPANY SNAPSHOT 19.23.2 PIPELINE PRODUCT PORTFOLIO 19.23.3 RECENT DEVELOPMENTS 19.24 XYPHOS (A SUBSIDIARY OF ASTELLAS PHARMA INC.) 19.24.1 COMPANY SNAPSHOT 19.24.2 REVENUE ANALYSIS 19.24.3 PIPELINE PRODUCT PORTFOLIO 19.24.4 RECENT DEVELOPMENTS 19.25 ZIOPHARM ONCOLOGY, INC. 19.25.1 COMPANY SNAPSHOT 19.25.2 PRODUCT PORTFOLIO 19.25.3 RECENT DEVELOPMENTS 20 QUESTIONNAIRE 21 RELATED REPORTSSegmentation
Short Description North America CAR-T Cell Therapy Treatment Market, By Product (Autologous CAR-T Cells, Allogeneic CAR-T Cells), Structure (First Generation CAR-T Cells, Second Generation Car-T Cells, Third Generation CAR-T Cells, Fourth Generation CAR-T Cells), Targeted Antigens (Antigens on Solid Tumors, Antigens on Hematologic Malignancies, Others), Brand (Yescarta, Kymriah, Tecartus, Others), Therapeutic Application (Hematological Malignancies, Pancreatic Cancer, Breast Cancer, Lung Cancer, Gastric Cancer, Multiple Myeloma, Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B-Cell Lymphoma, Acute Lymphoblastic Leukemia, Others), End User (Hospitals, Specialty Clinics, Others), Distribution Channel (Hospitals Pharmacy, Others), Country (U.S, Canada and Mexico) Industry Trends and Forecast to 2028 Market Definition: CAR-T cell therapy or chimeric antigen receptor T cells are those T cells which are genetically engineered in order to produce an artificial T-cell receptor which can be used as an immunotherapy for the treatment of various cancers. Chimeric antigen receptors are those receptor proteins that have been engineered in the laboratories to provide the T-cells with the novel ability to target a specific protein. Market Segmentation: The CAR-T cell therapy treatment market is segmented on the basis of the product, structure, targeted antigens, brand, therapeutic application, end user and distribution channel. On the basis of product, the CAR-T cell therapy treatment market is segmented into autologous CAR-T cells and allogeneic CAR-T cells On the basis of structure, the CAR-T cell therapy treatment market is segmented into first generation CAR-T cells, second generation CAR-T cells, third generation CAR-T cells and fourth generation CAR-T cells On the basis of targeted antigens, the CAR-T cell therapy treatment market is segmented into antigens on solid tumors, antigens on hematologic malignancies and others On the basis of brand, the CAR-T cell therapy treatment market is segmented into yescarta, kymriah, tecartus and others On the basis of therapeutic application, the CAR-T cell therapy treatment market is segmented into hematological malignancies, pancreatic cancer, breast cancer, lung cancer, gastric cancer, multiple myeloma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, acute lymphoblastic leukemia and others On the basis of end user, the CAR-T cell therapy treatment market is segmented into hospitals, specialty clinics and others On the basis of distribution channel, the CAR-T cell therapy treatment market is segmented into hospitals pharmacy and others Market Players: The key market players for North America CAR-T cell therapy treatment market are listed below: Atara Biotherapeutics, Inc. Amgen Inc. Bellicum Phamaceuticals, Inc. bluebird bio, inc. Adaptimmune Therapeutics plc. Bristol-Myers Squibb Company Xyphos (A Subsidiary of Astellas Pharma Inc.) Johnson & Johnson Services, Inc BioAtla Inc. Novartis AG Kite Pharma (A Subsidiary of Gilead Sciences, Inc.) Aurora Biopharma Tmunity Therapeutics Cartherics Pty ltd Ziopharm Oncology, Inc. Cellectis Mustang Bio Sorrento Therapeutics, Inc. TC BIOPHARM Celyad Oncology Tessa Therapeutics LtdMethodology
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